Analysis of systemic serum vancomycin levels following intraarticular application in primary total joint arthroplasty

Stauss R, Savov P, Seeber GH, Brand S, Ettinger M, Beheshty JA · 2024

Read Analysis of systemic serum vancomycin levels following intraarticular application in primary total joint arthroplasty by Stauss R, Savov P, Seeber GH, Brand S, Ettinger M, Beheshty JA (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11655570.txt.

Description

Stauss and five co-authors measure blood levels of vancomycin after the antibiotic powder is placed inside new hip and knee joints, in work from 2024. Surgeons dust the prosthesis with the drug to prevent joint infection, but how much reaches the bloodstream was unclear. One gram was applied in 103 primary operations, and blood was drawn at one and two days.

Hip patients showed low but real blood levels, while knee patients showed none at all. No patient reached drug treatment levels, and no side effects appeared. The authors judge the practice safe on this evidence and cheap insurance against a costly complication.

Catalog record

CREATORStauss R, Savov P, Seeber GH, Brand S, Ettinger M, Beheshty JA
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE19 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11655570

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