Single-Molecule Tracking dataset for histone H3 (hht1) from live and fixed cells of Schizosaccharomyces pombe

Akriti Kumari, Nitesh Kumar Podh, Sucharita Sen, Kirti Kashyap, Sahil Islam, Anupam Gupta, Eerappa Rajakumara, Mridula Nambiar, Gunjan Mehta · 2024

Read Single-Molecule Tracking dataset for histone H3 (hht1) from live and fixed cells of Schizosaccharomyces pombe by Akriti Kumari, Nitesh Kumar Podh, Sucharita Sen, Kirti Kashyap, Sahil Islam, Anupam Gupta, Eerappa Rajakumara, Mridula Nambiar, Gunjan Mehta (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11655555.txt.

Description

Akriti Kumari and co-authors released this 2024 data set tracking single protein molecules inside fission yeast. Watching one molecule at a time shows how proteins move in living cells with fine detail. The method is common in other model systems but had not been used in this yeast. The team tracked a histone protein that binds DNA packaging.

The data cover the histone in live and fixed cells, plus a free-floating green marker protein as a baseline. From the tracks, users can compute speed of spread, time bound, and the share of bound molecules. Those numbers help tell DNA-bound proteins from free ones in any new study. The set also serves to test tracking software and train machine learning tools.

Catalog record

CREATORAkriti Kumari, Nitesh Kumar Podh, Sucharita Sen, Kirti Kashyap, Sahil Islam, Anupam Gupta, Eerappa Rajakumara, Mridula Nambiar, Gunjan Mehta
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE40 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11655555

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