Identifying the key regulators orchestrating Epstein-Barr virus reactivation

Yaohao Wang, Jingwen Yu, Yonggang Pei · 2024

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Description

Wang, Yu, and Pei review switches that wake a common dormant virus. Epstein-Barr virus infects more than nine in ten people worldwide. It hides in hosts for life and can wake at times. Wake-up starts viral gene use and new virus output.

Many factors and pathways cross-talk to set that wake call. Host cell innate defenses push back on the process too. The review sums up early gene control at text and post-text steps. It covers viral factors for DNA copying and progeny build. It also maps how viral proteins blunt host defenses. Clear maps may point to drugs that lock dormancy.

Catalog record

CREATORYaohao Wang, Jingwen Yu, Yonggang Pei
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE42 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11655498

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