Case report: Multiphenotypic cervical cancer resembling human papillomavirus-related multiphenotypic sinonasal carcinoma

Xiaoxiao Bao, Yan Chen, Jing Zhang, Xiaowei Zhang · 2024

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Description

Xiaoxiao Bao and co-authors report a cervical cancer that closely resembled a rare HPV-related tumor of the nasal cavity, published in 2024. That tumor type is a two-part epithelial growth tied to human papillomavirus infection. It almost always arises in the nose or sinuses; only two cases elsewhere, in breast and vulva, had been reported.

A 69-year-old woman came to hospital after more than a year of vaginal bleeding and tested positive for high-risk HPV. Biopsy showed a high-grade lesion with invasion, and she had radical surgery. Pathology, staining tests, and HPV testing led to the diagnosis of a multiphenotypic cervical carcinoma resembling the nasal tumor. She received no added radiation or chemotherapy. After a year of follow-up there was no recurrence or spread. The authors note these tumors tend toward slow local growth despite high-grade looks.

Catalog record

CREATORXiaoxiao Bao, Yan Chen, Jing Zhang, Xiaowei Zhang
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE18 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11655235

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