Synthesis of β‐Alanine From Isoleucine and Propionate Catabolism via Aminotransferases
Margo H. Goldfarb, Joseph Boesel, Kai C. Wilczewski‐Shirai, Peter Reinhart, Trenton Scherger, Chloe Webb, Morgan Newlun, Kerry A. Rouhier · 2024
Read Synthesis of β‐Alanine From Isoleucine and Propionate Catabolism via Aminotransferases by Margo H. Goldfarb, Joseph Boesel, Kai C. Wilczewski‐Shirai, Peter Reinhart, Trenton Scherger, Chloe Webb, Morgan Newlun, Kerry A. Rouhier (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11655180.txt.
Description
Margo Goldfarb and co-authors present a 2024 study on how plants make beta-alanine, a small building block with many jobs. In plants it helps answer stresses such as drought, heat, and flooding. It also feeds into making vitamin B5 and coenzyme A, two vital molecules.
Plants can build beta-alanine from several starting materials, unlike bacteria, which use one route. Working with a model plant, the team fed labeled forms of isoleucine and propionate to cells. Tracking the labels showed both feed into beta-alanine through a shared middle step. They then found three enzymes, all aminotransferases, that can run the final step of that route. The work links amino acid breakdown to a wider stress and vitamin network.
Catalog record
| CREATOR | Margo H. Goldfarb, Joseph Boesel, Kai C. Wilczewski‐Shirai, Peter Reinhart, Trenton Scherger, Chloe Webb, Morgan Newlun, Kerry A. Rouhier |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 38 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |