Revisiting negative pressure wound therapy from a mechanobiological perspective supported by clinical and pathological data

Amit Gefen, Serena Russo, Marino Ciliberti · 2024

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Description

Amit Gefen, Serena Russo, and Marino Ciliberti revisit in 2024 how vacuum wound therapy really works. The therapy seals a wound under a dressing and applies gentle suction, and it is used on surgical cuts and stubborn wounds worldwide. Sales and clinical reports grew fast, but study of the mechanism lagged, and some early beliefs were wrong.

The authors explain healing through strain: the suction deforms tissue, and cells read that pull as a signal to grow and close the wound. Different dressing types pass the strain to tissue in different ways, which changes the effect. Knowing this, clinicians can pick formats that suit the wound and use the therapy more wisely.

Catalog record

CREATORAmit Gefen, Serena Russo, Marino Ciliberti
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE53 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11655127

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