A large-scale proteomics resource of circulating extracellular vesicles for biomarker discovery in pancreatic cancer
Bruno Bockorny, Lakshmi Muthuswamy, Ling Huang, Marco Hadisurya, Christine Maria Lim, Leo L Tsai, Ritu R Gill, Jesse L Wei, Andrea J Bullock, Joseph E Grossman, Robert J Besaw, Supraja Narasimhan, Weiguo Andy Tao, Sofia Perea, Mandeep S Sawhney, Steven D Freedman, Manuel Hildago, Anton Iliuk, Senthi · 2024
Read A large-scale proteomics resource of circulating extracellular vesicles for biomarker discovery in pancreatic cancer by Bruno Bockorny, Lakshmi Muthuswamy, Ling Huang, Marco Hadisurya, Christine Maria Lim, Leo L Tsai, Ritu R Gill, Jesse L Wei, Andrea J Bullock, Joseph E Grossman, Robert J Besaw, Supraja Narasimhan, Weiguo Andy Tao, Sofia Perea, Mandeep S Sawhney, Steven D Freedman, Manuel Hildago, Anton Iliuk, Senthi (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11655061.txt.
Description
Bruno Bockorny leads a large team building a protein atlas of blood-borne vesicles for pancreatic cancer detection, in a resource paper from two thousand twenty-four. Pancreatic cancer has the worst prognosis of common tumors, largely because diagnosis comes late. Liquid biopsies from extracellular vesicles hold out a chance of an early signal.
The test is to split cancer vesicles from those shed in benign disease. Chronic pancreatitis and precancerous cysts make hard controls that are of real use. A high-efficiency isolation method called EVtrap harvested vesicles from plasma for the team. Deep proteomics set out the cargo they carry in a catalog. The resource is meant for biomarker discovery across the field, and earlier detection is the hope that rides on it.
Catalog record
| CREATOR | Bruno Bockorny, Lakshmi Muthuswamy, Ling Huang, Marco Hadisurya, Christine Maria Lim, Leo L Tsai, Ritu R Gill, Jesse L Wei, Andrea J Bullock, Joseph E Grossman, Robert J Besaw, Supraja Narasimhan, Weiguo Andy Tao, Sofia Perea, Mandeep S Sawhney, Steven D Freedman, Manuel Hildago, Anton Iliuk, Senthi |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 77 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |