Effect of Bilateral Subthalamic Nucleus (STN) Deep Brain Stimulation (DBS) on drug reduction for Parkinson’s Disease: A retrospective observational study from Pakistan
Zubair Mustafsa Khan, Shahzeb Ahmad, Haseeb Mehmood Qadri, Ahtesham Khizar, Asif Bashir · 2024
Read Effect of Bilateral Subthalamic Nucleus (STN) Deep Brain Stimulation (DBS) on drug reduction for Parkinson’s Disease: A retrospective observational study from Pakistan by Zubair Mustafsa Khan, Shahzeb Ahmad, Haseeb Mehmood Qadri, Ahtesham Khizar, Asif Bashir (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11654648.txt.
Description
Zubair Khan and co-authors study how deep brain stimulation affects drug use in Parkinson's disease in Pakistan. Their 2024 study is set at a neurosurgery unit in Lahore. Forty nine patients were included. Each had stimulation of a small brain target on both sides. Care ran from 2018 to 2023. Data came from records and from interview based questionnaires. The study is framed as relevant to a low to middle income setting.
Drug dose, in levodopa equivalent terms, fell by fifty five point zero three percent after surgery. A motor score improved by eighty point four nine percent. Both results were highly significant. Time spent with involuntary movements fell by seventeen point five four percent. Time spent in off periods, when drugs fail, fell by twenty two point four four percent. A score for movement complications barely changed. The authors support the surgery in early disease.
Catalog record
| CREATOR | Zubair Mustafsa Khan, Shahzeb Ahmad, Haseeb Mehmood Qadri, Ahtesham Khizar, Asif Bashir |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 17 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |