Epidemiological and genetic characteristics of clinical carbapenemase-producing Enterobacterales isolates from Batna hospitals in Algeria

Amel Benbouza, Ahmed Kassah-Laouar, Widad Chelaghma, Fayza Bouziane, Yassina Mebarki, Jean-Marc Rolain, Lotfi Loucif · 2024

Read Epidemiological and genetic characteristics of clinical carbapenemase-producing Enterobacterales isolates from Batna hospitals in Algeria by Amel Benbouza, Ahmed Kassah-Laouar, Widad Chelaghma, Fayza Bouziane, Yassina Mebarki, Jean-Marc Rolain, Lotfi Loucif (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11654383.txt.

Description

Benbouza and co-authors map drug resistant gut germs in a 2024 study from three hospitals in Batna, Algeria. The germs at issue make enzymes that break down carbapenem drugs, a last line class of antibiotics. From 2016 to 2019 the team gathered over five thousand samples from patients. They named each germ, tested drug response, and read the genes behind the resistance.

Of the samples, 201 resisted carbapenem drugs, and 179 of those made the enzymes. Klebsiella pneumoniae led the list, with Escherichia coli and Enterobacter cloacae next. One gene family showed up in 82 percent of the positive samples. Pairs and triples of resistance genes also appeared, a first report for Algeria. The picture helps local doctors track a threat that raises death rates in hospitals.

Catalog record

CREATORAmel Benbouza, Ahmed Kassah-Laouar, Widad Chelaghma, Fayza Bouziane, Yassina Mebarki, Jean-Marc Rolain, Lotfi Loucif
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE42 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11654383

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