Integrative Proteomics and Phosphoproteomics Profiling of Symptomatic Accessory Navicular Bone Based on Tandem Mass Tag Technology
Bin Liu, Ran Wei, Yuqing Wang, Zishen Cheng, Liangliang Jiang, Xiaopeng Pu, Yaxing Zhang, Yantao Wang, Qiangjun Kang · 2024
Read Integrative Proteomics and Phosphoproteomics Profiling of Symptomatic Accessory Navicular Bone Based on Tandem Mass Tag Technology by Bin Liu, Ran Wei, Yuqing Wang, Zishen Cheng, Liangliang Jiang, Xiaopeng Pu, Yaxing Zhang, Yantao Wang, Qiangjun Kang (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11653880.txt.
Description
An extra bone beside the foot's navicular is common and usually silent, but in athletes it can turn training into injury. Bin Liu and eight co-authors compare the proteins of that extra bone with normal bone in 2024, from five injured patients after three months of training. They count both the proteins present and the chemical tags that switch them.
One hundred forty-seven proteins differed, pointing at cell adhesion and the scaffolding between cells, with two collagen genes as the busiest hubs. Five tagged proteins differed too, tied to fat handling in fat cells. Inflammation, bone repair, and bone balance proteins all appear in the pattern. The authors offer the map as a first molecular account of the injury and a guide for treatment.
Catalog record
| CREATOR | Bin Liu, Ran Wei, Yuqing Wang, Zishen Cheng, Liangliang Jiang, Xiaopeng Pu, Yaxing Zhang, Yantao Wang, Qiangjun Kang |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |