Topical insulin used alone or in combination with drug-depository contact lens for refractory cases of neurotrophic keratopathy
Alessandra Mancini, Maura Mancini, Andrea Taloni, Luca Bifezzi, Maria Angela Romeo, Lorenzo Rijillo, Mario Verdiglione, Vincenzo Scorcia, Pasquale Aragona, Giuseppe Giannaccare · 2024
Read Topical insulin used alone or in combination with drug-depository contact lens for refractory cases of neurotrophic keratopathy by Alessandra Mancini, Maura Mancini, Andrea Taloni, Luca Bifezzi, Maria Angela Romeo, Lorenzo Rijillo, Mario Verdiglione, Vincenzo Scorcia, Pasquale Aragona, Giuseppe Giannaccare (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11652743.txt.
Description
Alessandra Mancini and nine co-workers wrote a 2024 case series on insulin eye drops for a stubborn corneal disease where surface nerves fail. Standard care had already failed these patients. Nine eyes from eight patients joined across centers. All got insulin drops four times daily.
Some also wore a special contact lens that stores and releases the drug. Every corneal defect closed fully, in about twenty-six days on average. Healing speed was like in both arms of care. The drops alone closed defects slightly faster per day, without a firm gap. The authors present insulin as a workable rescue option.
Catalog record
| CREATOR | Alessandra Mancini, Maura Mancini, Andrea Taloni, Luca Bifezzi, Maria Angela Romeo, Lorenzo Rijillo, Mario Verdiglione, Vincenzo Scorcia, Pasquale Aragona, Giuseppe Giannaccare |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |