Protective effects of Pelargonium graveolens (geranium) oil against cefotaxime-induced hepato-renal toxicity in rats
Shaimaa M. Azzam, Heba M. A. Elsanhory, Ahmed H. Abd El-Slam, Marwa S. M. Diab, Halima Mohamed Ibrahim, Abdalrahman Mohammed Yousef, Fatma Mahmoud Sabry, Ebtihal Y. Khojah, Somaiah A. Bokhari, Gad Elsayed Mohamed Salem, Marwa Saad Zaghloul · 2024
Read Protective effects of Pelargonium graveolens (geranium) oil against cefotaxime-induced hepato-renal toxicity in rats by Shaimaa M. Azzam, Heba M. A. Elsanhory, Ahmed H. Abd El-Slam, Marwa S. M. Diab, Halima Mohamed Ibrahim, Abdalrahman Mohammed Yousef, Fatma Mahmoud Sabry, Ebtihal Y. Khojah, Somaiah A. Bokhari, Gad Elsayed Mohamed Salem, Marwa Saad Zaghloul (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11652510.txt.
Description
The antibiotic cefotaxime saves lives but can injure the liver and kidneys. Shaimaa Azzam and co-authors tested in 2024 whether geranium oil shields rats from that damage.
Thirty rats were split into five groups: controls, antibiotic alone, oil alone, and the combination. After fourteen days, rats on the antibiotic alone showed the expected harm in blood markers and tissue samples. Rats also given the oil fared far better: liver enzymes and kidney markers dropped, inflammation signals fell, and protective compounds recovered. Microscope and staining checks confirmed healthier tissue. The authors conclude the oil blunts the drug's collateral damage.
Catalog record
| CREATOR | Shaimaa M. Azzam, Heba M. A. Elsanhory, Ahmed H. Abd El-Slam, Marwa S. M. Diab, Halima Mohamed Ibrahim, Abdalrahman Mohammed Yousef, Fatma Mahmoud Sabry, Ebtihal Y. Khojah, Somaiah A. Bokhari, Gad Elsayed Mohamed Salem, Marwa Saad Zaghloul |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 49 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |