Assessment of cerebral perfusion alterations in dementia with Lewy bodies and Alzheimer’s disease

Yanlai Xia, Huanjing Jiao, Junling Han, Ying Guo, Xiaoxi Niu, Yong Ji, Hongyan Ni · 2024

Read Assessment of cerebral perfusion alterations in dementia with Lewy bodies and Alzheimer’s disease by Yanlai Xia, Huanjing Jiao, Junling Han, Ying Guo, Xiaoxi Niu, Yong Ji, Hongyan Ni (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11652026.txt.

Description

Yanlai Xia and co-authors compare brain blood flow in two common forms of dementia, to find measures that tell them apart, published in 2024. Dementia with Lewy bodies and Alzheimer's disease share many symptoms, so telling them apart in the clinic is hard. Blood flow imaging may give signs that help with that call.

Patients with each disease, plus healthy controls, had thinking tests and a special MRI scan of brain perfusion. The Lewy body group showed lower flow across frontal, parietal, and temporal areas, plus one rear area. The Alzheimer's group also showed lower flow in wide areas. The team tested how well flow measures and transit time separate the two diseases, and how flow relates to scores on standard thinking tests.

Catalog record

CREATORYanlai Xia, Huanjing Jiao, Junling Han, Ying Guo, Xiaoxi Niu, Yong Ji, Hongyan Ni
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE32 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11652026

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