Reproducibility of proton density fat fraction assessment of thigh muscle in a multi-site, multi-vendor cohort study at 10 years after anterior cruciate ligament reconstruction

Brendan L. Eck, Sibaji Gaj, Richard Lartey, Mei Li, Jeehun Kim, Carl S. Winalski, William Zaylor, Dongxing Xie, Ria Tilve, Kevin D. Harkins, Bruce M. Damon, Laura J. Huston, Faysal Altahawi, Nancy A. Obuchowski, Xiaodong Zhong, Kecheng Liu, Harry Friel, Dimitrios C. Karampinos, Michael V. Knopp, Mor · 2024

Read Reproducibility of proton density fat fraction assessment of thigh muscle in a multi-site, multi-vendor cohort study at 10 years after anterior cruciate ligament reconstruction by Brendan L. Eck, Sibaji Gaj, Richard Lartey, Mei Li, Jeehun Kim, Carl S. Winalski, William Zaylor, Dongxing Xie, Ria Tilve, Kevin D. Harkins, Bruce M. Damon, Laura J. Huston, Faysal Altahawi, Nancy A. Obuchowski, Xiaodong Zhong, Kecheng Liu, Harry Friel, Dimitrios C. Karampinos, Michael V. Knopp, Mor (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11651994.txt.

Description

Brendan Eck and co-authors test, in 2024, whether a scanning method for muscle fat gives the same answer across hospitals and machine brands. The method estimates fat fraction inside thigh muscle from a special MRI sequence and could serve as a marker of muscle quality. Patients were scanned ten years after knee ligament surgery, across three sites and two vendors.

Scanning was harmonized and analysis centralized. Phantom tests picked the most stable algorithm, and a new correction step fixed scaling errors seen on some machines. Traveling volunteers checked consistency in people. The setup aims to compare operated and unoperated legs credibly in a long-term multicenter follow-up.

Catalog record

CREATORBrendan L. Eck, Sibaji Gaj, Richard Lartey, Mei Li, Jeehun Kim, Carl S. Winalski, William Zaylor, Dongxing Xie, Ria Tilve, Kevin D. Harkins, Bruce M. Damon, Laura J. Huston, Faysal Altahawi, Nancy A. Obuchowski, Xiaodong Zhong, Kecheng Liu, Harry Friel, Dimitrios C. Karampinos, Michael V. Knopp, Mor
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE51 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11651994

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