Sex-based differences in CEACAM5 expression in lung cancer
Gavitt A. Woodard, Emma R. Kane, Nicholas Todorovic, Samantha Prince, Sanja Dacic, Lieping Chen · 2024
Read Sex-based differences in CEACAM5 expression in lung cancer by Gavitt A. Woodard, Emma R. Kane, Nicholas Todorovic, Samantha Prince, Sanja Dacic, Lieping Chen (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11651760.txt.
Description
Gavitt Woodard and five co-authors study a tumor marker in lung cancer in a paper from two thousand twenty-four. The protein, CEACAM5, appears in about a fifth to a quarter of non-small cell lung cancers. It draws interest as a possible blood test marker and drug target.
Using cancer atlas data on nearly one thousand tumors, they compared expression by sex and tumor type. Women showed higher levels than men, and one subtype, adenocarcinoma, showed far higher levels than the other main type. High levels did not predict survival overall. Among women with early-stage adenocarcinoma, though, high levels tied to worse survival. The authors call for more study of how sex shapes this marker's use.
Catalog record
| CREATOR | Gavitt A. Woodard, Emma R. Kane, Nicholas Todorovic, Samantha Prince, Sanja Dacic, Lieping Chen |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 19 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |