Multi-omics decipher the immune microenvironment and unveil therapeutic strategies for postoperative ovarian cancer patients
Zhibing Liu, Fei Wang, Weiwei Chen, Yujie Zhai, Jinbo Jian, Xiaole Wang, Yingjiang Xu, Jiajia An, Lei Han · 2024
Read Multi-omics decipher the immune microenvironment and unveil therapeutic strategies for postoperative ovarian cancer patients by Zhibing Liu, Fei Wang, Weiwei Chen, Yujie Zhai, Jinbo Jian, Xiaole Wang, Yingjiang Xu, Jiajia An, Lei Han (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11651737.txt.
Description
Liu and eight co-authors present a study from twenty twenty-four on cell death patterns in ovarian cancer after surgery. This cancer is aggressive, often found late, and prone to relapse. Cell death patterns may signal outlook and drug response after surgery. The team build a new grouping from twelve programmed death patterns. Data come from large cancer genome sets and single-cell sources. One patient cluster shows high immune signals and therapy sensitivity. A death index from eight genes splits patients by outlook.
Patients with a high index fare worse after surgery. Low-index patients may respond better to immune therapy. High-index patients may respond better to a class of targeted drugs instead. The authors offer a chart to predict outlook and drug fit.
Catalog record
| CREATOR | Zhibing Liu, Fei Wang, Weiwei Chen, Yujie Zhai, Jinbo Jian, Xiaole Wang, Yingjiang Xu, Jiajia An, Lei Han |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |