Whole brain functional connectivity: Insights from next generation neural mass modelling incorporating electrical synapses
Michael Forrester, Sammy Petros, Oliver Cattell, Yi Ming Lai, Reuben D. O’Dea, Stamatios Sotiropoulos, Stephen Coombes · 2024
Read Whole brain functional connectivity: Insights from next generation neural mass modelling incorporating electrical synapses by Michael Forrester, Sammy Petros, Oliver Cattell, Yi Ming Lai, Reuben D. O’Dea, Stamatios Sotiropoulos, Stephen Coombes (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11651611.txt.
Description
Michael Forrester, Sammy Petros, Oliver Cattell, Yi Ming Lai, Reuben O'Dea, Stamatios Sotiropoulos, and Stephen Coombes wrote a 2024 paper on simulating the whole brain's activity. Such models place a small activity unit at each brain region and link them by the brain's wiring. A newer unit type, derived exactly from spiking cell models, can also include fast electrical links between cells, not just chemical ones.
Using wiring data from the Human Connectome Project, the team tested whether the model makes the linked activity patterns seen in real brain scans. It did produce patterns of the observed kind. A math analysis of the network's steady state explained part of the pattern at each frequency. The work sharpens tools for studying brain rhythms without invasive tests.
Catalog record
| CREATOR | Michael Forrester, Sammy Petros, Oliver Cattell, Yi Ming Lai, Reuben D. O’Dea, Stamatios Sotiropoulos, Stephen Coombes |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 61 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |