Causal relationships between depression, emotional changes, and hiatal hernia: A Mendelian randomization analysis

Chaofan Pan, Mingzhi Lin, Wenbin Luo, Ruoyun Li, Changjiang Luo · 2024

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Description

Chaofan Pan and co-authors test whether low mood can cause hiatal hernia, a condition where part of the stomach slips up through the diaphragm, in a 2024 study. Mood and gut problems often travel together, but cause and effect are hard to separate.

The team used a genetic method that treats inherited variants as natural experiments. Mood swings, depression, tension, and misery each raised the odds of the hernia slightly. The reverse test found no sign that the hernia worsens mood. All four feelings pointed the same way across several checks. The authors say hernia care and prevention should take mental health seriously.

Catalog record

CREATORChaofan Pan, Mingzhi Lin, Wenbin Luo, Ruoyun Li, Changjiang Luo
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE18 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11651434

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