Effectiveness and Safety of Shenxiong Huanglian Detoxification Granule Combined with Donepezil for the Treatment of Alzheimer’s Disease: Study Protocol for a Multicenter, Pragmatic, Randomized Controlled Clinical Trial

Jian Lin, Xinghua Liu, Xi Lin, Nanyang Liu, Hui Pei, Yichun Zhao, Guran Yu, Wei Wang, Chuan Chen, Tingting Hou, Xun Li, Xingdong Lin, Hao Li · 2024

Read Effectiveness and Safety of Shenxiong Huanglian Detoxification Granule Combined with Donepezil for the Treatment of Alzheimer’s Disease: Study Protocol for a Multicenter, Pragmatic, Randomized Controlled Clinical Trial by Jian Lin, Xinghua Liu, Xi Lin, Nanyang Liu, Hui Pei, Yichun Zhao, Guran Yu, Wei Wang, Chuan Chen, Tingting Hou, Xun Li, Xingdong Lin, Hao Li (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11651136.txt.

Description

Jian Lin and co-authors publish the protocol for a trial combining a Chinese herbal granule with a standard Alzheimer drug in a 2024 paper. The degenerative disease causes progressive memory and thinking loss, and cases are rising with population aging. Earlier studies suggest combining traditional and Western medicine helps.

The multicenter, pragmatic randomized trial will assign nearly four hundred people with mild to moderate disease to the combination or control care. Outcomes track changes in cognitive scores, daily function, and safety. The protocol sets out eligibility, dosing, and analysis plans in advance of results.

Catalog record

CREATORJian Lin, Xinghua Liu, Xi Lin, Nanyang Liu, Hui Pei, Yichun Zhao, Guran Yu, Wei Wang, Chuan Chen, Tingting Hou, Xun Li, Xingdong Lin, Hao Li
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE36 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11651136

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