The Correlation Analysis Between m6A Methylation Modification and Ferroptosis Induced by Cigarette Smoke in Human Bronchial Epithelium
Xiaomei Duan, Tingting Hu, Lijuan Xu, Zheng Li, Jing Jing, Dan Xu, Jianbing Ding, Fengsen Li, Min Jiang, Jing Wang · 2024
Read The Correlation Analysis Between m6A Methylation Modification and Ferroptosis Induced by Cigarette Smoke in Human Bronchial Epithelium by Xiaomei Duan, Tingting Hu, Lijuan Xu, Zheng Li, Jing Jing, Dan Xu, Jianbing Ding, Fengsen Li, Min Jiang, Jing Wang (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11650891.txt.
Description
Xiaomei Duan and co-authors link a chemical tag on RNA to an iron-driven cell death in smoke-damaged airways in a 2024 study. The lung disease COPD grows out of long airway inflammation, and cigarette smoke is its main driver. Both the cell death type and the RNA tag connect to inflammation diseases.
Mining two public gene data sets gave 529 changed genes in COPD. In airway cells exposed to smoke extract, the team measured rust-like damage markers and iron levels. Genes tied to the death process and one enzyme that removes the RNA tag shifted in step. The pattern supports a real link worth testing as a treatment angle.
Catalog record
| CREATOR | Xiaomei Duan, Tingting Hu, Lijuan Xu, Zheng Li, Jing Jing, Dan Xu, Jianbing Ding, Fengsen Li, Min Jiang, Jing Wang |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |