Efficacy of mesenchymal stem cells in the treatment of peritoneal fibrosis in animal models: a systematic review and meta-analysis
Lingqian Zheng, Wenmin Chen, Kaijin Yao, Yina Xie, Chunling Liao, Yongda Lin, Tianbiao Zhou · 2024
Read Efficacy of mesenchymal stem cells in the treatment of peritoneal fibrosis in animal models: a systematic review and meta-analysis by Lingqian Zheng, Wenmin Chen, Kaijin Yao, Yina Xie, Chunling Liao, Yongda Lin, Tianbiao Zhou (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11650619.txt.
Description
Lingqian Zheng and colleagues pool animal studies to test if stem cells can ease a scarring disease of the belly lining, in this review from twenty twenty-four. The disease, peritoneal fibrosis, is a known risk of long-term dialysis through the belly, and it can force patients to stop that therapy. Mesenchymal stem cells are prized for calming inflammation and slowing scars.
The team searched four databases and found 15 animal studies that fit. Across them, stem cell treatment lowered key inflammation signals and cut collagen, the stuff of scars. The lining grew thinner toward normal, and fluid removal through it improved. A few measures did not change: one growth factor, and some salt and waste ratios. Since all the work is in animals, the authors frame the cells as a hope to test in people, not a proven cure.
Catalog record
| CREATOR | Lingqian Zheng, Wenmin Chen, Kaijin Yao, Yina Xie, Chunling Liao, Yongda Lin, Tianbiao Zhou |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 49 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |