Non-covalent organocatalyzed enantioselective cyclization reactions of α,β-unsaturated imines
Sergio Torres-Oya, Mercedes Zurro · 2024
Read Non-covalent organocatalyzed enantioselective cyclization reactions of α,β-unsaturated imines by Sergio Torres-Oya, Mercedes Zurro (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11650568.txt.
Description
Sergio Torres-Oya and Mercedes Zurro review a green route to handed molecules, in a 2024 paper. Many useful compounds exist as mirror images, and making only the wanted hand is a core skill in chemistry. Ring-forming reactions of nitrogen-bearing building blocks called 1-azadienes can yield valuable ring systems in one atom-thrifty step.
The review covers recent advances in running those cyclizations with organocatalysts, small carbon-based helpers that steer the reaction through gentle, non-bonded contacts rather than metals. Such catalysts can set the handedness of the products with high precision. The authors survey the strategies reported so far and the ring systems they reach. They frame the field as a cleaner path to the nitrogen rings that medicines and materials often need.
Catalog record
| CREATOR | Sergio Torres-Oya, Mercedes Zurro |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 45 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |