Lycopene’s therapeutic mechanisms in epididymitis: a network pharmacology and experimental study
Ming-Wei Zhan, Peng-Fei Liu, Zai-Hui Nie, Xu-Xin Zhan, Qiang Lou, Lei Wang, Jun-Jie Wu, Yi Yu, Xue-Jun Shang · 2024
Read Lycopene’s therapeutic mechanisms in epididymitis: a network pharmacology and experimental study by Ming-Wei Zhan, Peng-Fei Liu, Zai-Hui Nie, Xu-Xin Zhan, Qiang Lou, Lei Wang, Jun-Jie Wu, Yi Yu, Xue-Jun Shang (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11650350.txt.
Description
Ming-Wei Zhan and co-authors test lycopene, the red plant pigment in tomatoes, against a painful male tract illness, in work from 2024. The illness, epididymitis, often stems from plain infection. Standard drugs kill germs but cannot undo tissue harm or protect later fertility, so the team sought an added aid.
Database searches pointed to one cell pathway that steers swelling and cell death. In mice made ill with a germ toxin, lycopene eased tissue harm and cut key swelling signals. It also raised the strength of cell guards against oxygen strain. Docking tests backed a tight fit with the pathway targets.
Catalog record
| CREATOR | Ming-Wei Zhan, Peng-Fei Liu, Zai-Hui Nie, Xu-Xin Zhan, Qiang Lou, Lei Wang, Jun-Jie Wu, Yi Yu, Xue-Jun Shang |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |