Resolution of Fenfluramine-associated pulmonary arterial hypertension in Lennox-Gastaut syndrome: A case report and literature review
Rebecca Strafella, Richard Wang, Marissa Petchpradub, Ariel Sacknovitz, Patricia E McGoldrick, Steven M Wolf · 2024
Read Resolution of Fenfluramine-associated pulmonary arterial hypertension in Lennox-Gastaut syndrome: A case report and literature review by Rebecca Strafella, Richard Wang, Marissa Petchpradub, Ariel Sacknovitz, Patricia E McGoldrick, Steven M Wolf (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11650214.txt.
Description
A seizure drug revived from a banned diet pill gave one four year old dangerous heart pressure, then cleared when stopped, report Rebecca Strafella and co-authors in a 2024 case study. The girl had Lennox-Gastaut syndrome, a hard epilepsy, and started low dose fenfluramine after other treatments failed.
Six months in, scans found high pressure in the lung arteries and a leaking heart valve, though she felt fine. Two months off the drug, both had resolved. Restarted on it for seizures, she stayed clear at six months. The authors, reviewing the literature, back careful heart screening around the drug's use.
Catalog record
| CREATOR | Rebecca Strafella, Richard Wang, Marissa Petchpradub, Ariel Sacknovitz, Patricia E McGoldrick, Steven M Wolf |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 11 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |