Memantine-Assisted Treatment of N-Methyl-D-Aspartate Receptor Antibody Encephalitis: A Mini Review
Fei-Xiang Liu, Qi Qiu, Feng Yan, Yan-Chen Feng, Hong-Hui Wei, Xia Li · 2024
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Description
Fei-Xiang Liu and five co-authors weigh a common dementia drug as an add-on for autoimmune brain inflammation. Their 2024 mini review covers NMDA receptor antibody encephalitis. The disease brings seizures, confusion, and movement problems, and can sink into coma. Standard care uses immune therapy and tumor removal when present.
Memantine blocks the same receptor the antibodies attack. Case reports suggest it can ease symptoms in some patients. Yet blocking may also cut the receptors neurons need to talk. Five papers and eight case studies inform the balance. Timing, dose, and duration remain unsettled. The review calls for careful trials before memantine earns a firm place.
Catalog record
| CREATOR | Fei-Xiang Liu, Qi Qiu, Feng Yan, Yan-Chen Feng, Hong-Hui Wei, Xia Li |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 20 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |