A critical role of action-related functional networks in Gilles de la Tourette syndrome
Juan Carlos Baldermann, Jan Niklas Petry-Schmelzer, Thomas Schüller, Lin Mahfoud, Gregor A Brandt, Till A Dembek, Christina van der Linden, Joachim K Krauss, Natalia Szejko, Kirsten R Müller-Vahl, Christos Ganos, Bassam Al-Fatly, Petra Heiden, Domenico Servello, Tommaso Galbiati, Kara A Johnson, Chr · 2024
Read A critical role of action-related functional networks in Gilles de la Tourette syndrome by Juan Carlos Baldermann, Jan Niklas Petry-Schmelzer, Thomas Schüller, Lin Mahfoud, Gregor A Brandt, Till A Dembek, Christina van der Linden, Joachim K Krauss, Natalia Szejko, Kirsten R Müller-Vahl, Christos Ganos, Bassam Al-Fatly, Petra Heiden, Domenico Servello, Tommaso Galbiati, Kara A Johnson, Chr (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11649905.txt.
Description
Juan Carlos Baldermann and a large team of co-authors map the brain networks that matter in Tourette syndrome. Their study appeared in 2024. The syndrome brings unwanted movements and sounds called tics. Deep brain stimulation can ease severe tics, but the best networks to target were unclear. The team combined data from two stimulation cohorts and one group of patients whose tics came from brain lesions.
They mapped every stimulation site and lesion onto a wiring map built from a thousand healthy brains. Stronger tic relief came when stimulation sites connected well to networks for action control. One network, the cingulo-opercular, matched best. The pattern held in the second cohort. The authors say aiming at these networks could make stimulation therapy more reliable.
Catalog record
| CREATOR | Juan Carlos Baldermann, Jan Niklas Petry-Schmelzer, Thomas Schüller, Lin Mahfoud, Gregor A Brandt, Till A Dembek, Christina van der Linden, Joachim K Krauss, Natalia Szejko, Kirsten R Müller-Vahl, Christos Ganos, Bassam Al-Fatly, Petra Heiden, Domenico Servello, Tommaso Galbiati, Kara A Johnson, Chr |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 66 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |