Glucagon-like peptide-1 receptor agonists during pregnancy and lactation
Jonathan S. Zipursky, Tali Bogler, Cynthia Maxwell · 2024
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Description
Jonathan Zipursky, Tali Bogler, and Cynthia Maxwell give guidance in a 2024 article on gut hormone drugs during pregnancy and breastfeeding. The drugs treat diabetes, obesity, and a hormone disorder, and use is climbing fast. Patients who plan a pregnancy need clear rules on when to stop and what risks remain.
Animal studies showed birth defects and stunted growth at human like doses, so patients should stop the drugs one to two months before a planned pregnancy and use contraception while on them. Two small human studies found no rise in major birth defects after early exposure, though data stay thin. Stopping can bring back much of the lost weight within a year. The authors advise against use while breastfeeding.
Catalog record
| CREATOR | Jonathan S. Zipursky, Tali Bogler, Cynthia Maxwell |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 2 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |