A three-phase strategy of bionic drug reservoir scaffold by 3D printing and layer-by-layer modification for chronic relapse management in traumatic osteomyelitis
Yutong Zhang, Tongtong Xu, Tieshu Li, Hening Chen, Guangzhe Xu, Wenxin Hu, Yongting Li, Yue Dong, Zhihui Liu, Bing Han · 2024
Read A three-phase strategy of bionic drug reservoir scaffold by 3D printing and layer-by-layer modification for chronic relapse management in traumatic osteomyelitis by Yutong Zhang, Tongtong Xu, Tieshu Li, Hening Chen, Guangzhe Xu, Wenxin Hu, Yongting Li, Yue Dong, Zhihui Liu, Bing Han (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11648807.txt.
Description
Ten authors, led by Yutong Zhang, build in 2024 a staged bone implant to fight a stubborn bone infection that keeps relapsing after trauma. Their plan runs in three phases: a strong germ killing burst, a watch and bone growth phase, and full repair. A three dimensional printed scaffold with layered coatings serves as the drug store.
Two drugs ride inside: germ killing peptides that rush out fast, and a bone friendly drug that leaks over forty days. The frame's strength matched spongy bone in tests. Gel layers aping the natural membrane stage the release. Cell and animal work sits behind the design claims.
Catalog record
| CREATOR | Yutong Zhang, Tongtong Xu, Tieshu Li, Hening Chen, Guangzhe Xu, Wenxin Hu, Yongting Li, Yue Dong, Zhihui Liu, Bing Han |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 55 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |