Impact of Fusobacterium nucleatum in the treatment of cancer, including radiotherapy and its future potential in esophageal cancer
Manato Ohsawa, Hiromi Nishi, Manabu Emi, Toru Yoshikawa, Yoichi Hamai, Yuta Ibuki, Tomoaki Kurokawa, Ryosuke Hirohata, Nao Kitasaki, Miki Kawada-Matsuo, Hitoshi Komatsuzawa, Hiroyuki Kawaguchi, Morihito Okada · 2024
Read Impact of Fusobacterium nucleatum in the treatment of cancer, including radiotherapy and its future potential in esophageal cancer by Manato Ohsawa, Hiromi Nishi, Manabu Emi, Toru Yoshikawa, Yoichi Hamai, Yuta Ibuki, Tomoaki Kurokawa, Ryosuke Hirohata, Nao Kitasaki, Miki Kawada-Matsuo, Hitoshi Komatsuzawa, Hiroyuki Kawaguchi, Morihito Okada (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11647932.txt.
Description
Manato Ohsawa and twelve colleagues published a 2024 review on a bacterium, Fusobacterium nucleatum, and its influence on cancer treatment. The bacterium, normally found in the mouth, tends to clump and form biofilms, protective communities that shield microbes from drugs and the immune system.
Biofilm-forming microbes inside tumors can blunt the effectiveness of cancer treatments, including radiotherapy. Esophageal cancer still kills a large share of its patients despite combined surgery, chemotherapy, and radiation. The review examines how this bacterium affects those treatments and discusses its future potential role in esophageal cancer, whether as a target to attack, a marker of prognosis, or both. Understanding tumor microbes may open a new lever in cancer care.
Catalog record
| CREATOR | Manato Ohsawa, Hiromi Nishi, Manabu Emi, Toru Yoshikawa, Yoichi Hamai, Yuta Ibuki, Tomoaki Kurokawa, Ryosuke Hirohata, Nao Kitasaki, Miki Kawada-Matsuo, Hitoshi Komatsuzawa, Hiroyuki Kawaguchi, Morihito Okada |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |