The effect of hyperbaric oxygen therapy on oxidative stress and inflammation in patients with diabetic foot ulcers: A preliminary study
Nadia Mabel Pérez-Vielma, María Magdalena Valencia Gutiérrez, Jennifer Viridiana Sánchez Camacho, José Enrique González Hernández, Ángel Miliar García, César Ochoa, Jonathan Labovitz, Modesto Gómez López · 2024
Read The effect of hyperbaric oxygen therapy on oxidative stress and inflammation in patients with diabetic foot ulcers: A preliminary study by Nadia Mabel Pérez-Vielma, María Magdalena Valencia Gutiérrez, Jennifer Viridiana Sánchez Camacho, José Enrique González Hernández, Ángel Miliar García, César Ochoa, Jonathan Labovitz, Modesto Gómez López (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11647834.txt.
Description
Diabetic foot ulcers resist healing and can end in amputation; breathing pure oxygen under pressure is one add-on therapy. Nadia Pérez-Vielma and co-authors run a preliminary study of what that therapy does to inflammation and oxidative stress genes. Fifteen patients with mid-to-deep ulcers went through 30 chamber sessions.
Blood gene activity shifted after treatment. Two antioxidant defense genes rose, one of them threefold. Several inflammatory signals also rose, while one major one, TNF alpha, fell by half. Every patient's lesions fully closed. The mixed gene pattern suggests the therapy does not simply damp inflammation; it retunes it while boosting antioxidant cover. The authors link the changes to better blood vessel growth and circulation, and call for a larger controlled study.
Catalog record
| CREATOR | Nadia Mabel Pérez-Vielma, María Magdalena Valencia Gutiérrez, Jennifer Viridiana Sánchez Camacho, José Enrique González Hernández, Ángel Miliar García, César Ochoa, Jonathan Labovitz, Modesto Gómez López |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |