Fluctuation of physical function during chimeric antigen receptor T‐cell therapy during rehabilitation intervention: Real‐world data and risk factor analyses

Ryota Hamada, Yasuyuki Arai, Toshio Kitawaki, Naokazu Nakamura, Masanobu Murao, Michiko Matsushita, Junsuke Miyasaka, Tsugumi Asano, Tomoyasu Jo, Momoko Nishikori, Junya Kanda, Chisaki Mizumoto, Kouhei Yamashita, Ryosuke Ikeguchi, Akifumi Takaori‐Kondo · 2024

Read Fluctuation of physical function during chimeric antigen receptor T‐cell therapy during rehabilitation intervention: Real‐world data and risk factor analyses by Ryota Hamada, Yasuyuki Arai, Toshio Kitawaki, Naokazu Nakamura, Masanobu Murao, Michiko Matsushita, Junsuke Miyasaka, Tsugumi Asano, Tomoyasu Jo, Momoko Nishikori, Junya Kanda, Chisaki Mizumoto, Kouhei Yamashita, Ryosuke Ikeguchi, Akifumi Takaori‐Kondo (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11647737.txt.

Description

Ryota Hamada and co-authors track physical function through CAR T-cell therapy, a cancer treatment with a long timeline and heavy side effects. Published in 2024, the retrospective study follows seventy-seven patients who received rehabilitation during treatment. Exercise tolerance was read by the six minute walk test, before therapy and thirty days after infusion.

Median walking distance sat at about 450 meters at both readings, and the overall change was small and statistically loose. The therapy's storm phase, with fever syndromes and brain effects, did not sink average function under rehab cover. Regression work then hunted what did move the needle: age over sixty-five made little difference, while hemoglobin shifts entered the model. The authors map risk factors for decline.

Catalog record

CREATORRyota Hamada, Yasuyuki Arai, Toshio Kitawaki, Naokazu Nakamura, Masanobu Murao, Michiko Matsushita, Junsuke Miyasaka, Tsugumi Asano, Tomoyasu Jo, Momoko Nishikori, Junya Kanda, Chisaki Mizumoto, Kouhei Yamashita, Ryosuke Ikeguchi, Akifumi Takaori‐Kondo
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE28 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11647737

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