Incidence and risk factors of graft failure in allogeneic hematopoietic stem cell transplantation for mucopolysaccharidosis in a nationwide pediatric cohort. A study on behalf of the Francophone Society of Bone Marrow Transplantation and Cellular Therapy
Laura Danhardt, Arnaud Wiedemann, Gerard Michel, Jean‐Hugues Dalle, Fanny Rialland, Cécile Renard, Charlotte Jubert, Johan Maertens, Anne Sirvent, Nimrod Buchbinder, Christine Devalck, Bénédicte Brichard, Catherine Paillard, Stephanie Nguyen, Angelo Paci, David Combarel, Martin Castelle, Simona Pagl · 2024
Read Incidence and risk factors of graft failure in allogeneic hematopoietic stem cell transplantation for mucopolysaccharidosis in a nationwide pediatric cohort. A study on behalf of the Francophone Society of Bone Marrow Transplantation and Cellular Therapy by Laura Danhardt, Arnaud Wiedemann, Gerard Michel, Jean‐Hugues Dalle, Fanny Rialland, Cécile Renard, Charlotte Jubert, Johan Maertens, Anne Sirvent, Nimrod Buchbinder, Christine Devalck, Bénédicte Brichard, Catherine Paillard, Stephanie Nguyen, Angelo Paci, David Combarel, Martin Castelle, Simona Pagl (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11647734.txt.
Description
Laura Danhardt and co-authors study graft failure rates in stem cell transplants for children with mucopolysaccharidosis. These storage diseases need urgent treatment to protect the brain. Donor stem cell transplant remains the main option for most children.
Cord blood with gentler conditioning is now standard care. French centers lately reported worrying graft failure rates. A registry study across French-speaking centers gathered the facts. It aimed to find risks behind failed grafts. Results should help clinicians pick transplant platforms wisely. Outcomes after failure were also described for families. Gene therapy may help later, but access is limited now. The study strengthens today's transplant decisions for young patients.
Catalog record
| CREATOR | Laura Danhardt, Arnaud Wiedemann, Gerard Michel, Jean‐Hugues Dalle, Fanny Rialland, Cécile Renard, Charlotte Jubert, Johan Maertens, Anne Sirvent, Nimrod Buchbinder, Christine Devalck, Bénédicte Brichard, Catherine Paillard, Stephanie Nguyen, Angelo Paci, David Combarel, Martin Castelle, Simona Pagl |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 19 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |