Terminal deoxynucleotidyl transferase‐positive high‐grade B‐cell lymphoma with MYC and BCL2 rearrangements transformed from follicular lymphoma

Radu Chiriac, Lucile Baseggio, Marie Donzel · 2024

Read Terminal deoxynucleotidyl transferase‐positive high‐grade B‐cell lymphoma with MYC and BCL2 rearrangements transformed from follicular lymphoma by Radu Chiriac, Lucile Baseggio, Marie Donzel (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11647685.txt.

Description

Radu Chiriac, Lucile Baseggio, and Marie Donzel report a follicular lymphoma that changed into a far more aggressive form, in a 2024 paper. The man, aged forty eight, had reached full remission on antibody plus chemotherapy and was on upkeep therapy. He then came in with upper belly pain.

Blood tests showed a very high enzyme level and mild anemia, with odd lymphoma cells in the blood. Scans found a large mass behind the gut with strong tracer uptake. Cell tests showed a mature B cell growth with two key gene swaps and a marker more typical of young cell tumors. The case shows how a quiet lymphoma can transform, and why new pain in remission demands a fast, full workup.

Catalog record

CREATORRadu Chiriac, Lucile Baseggio, Marie Donzel
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE6 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11647685

Browse the full library · About the Tower of Babel