Antisense transcription is associated with expression of metal resistance determinants in Cupriavidus metallidurans CH34
Cornelia Große, Jan Grau, Martin Herzberg, Dietrich H Nies · 2024
Read Antisense transcription is associated with expression of metal resistance determinants in Cupriavidus metallidurans CH34 by Cornelia Große, Jan Grau, Martin Herzberg, Dietrich H Nies (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11647585.txt.
Description
Cornelia Große and co-authors map reverse read transcripts in a metal loving bacterium, in a 2024 study. The microbe thrives where metals abound yet also survives scarcity. Genes for metal defense switch on and off with supply, and the reverse reads may help tune them.
The team grew two strains under a mixed metal dose, a metal stripping agent, or no challenge, then read all transcripts both ways. More than ten thousand reverse reads were found; about thirteen hundred were long and active. Under metal stress, shifts in gene reads often came with matching reverse activity. Spot checks confirmed the pattern. The authors suggest reverse reads steady the pump genes' messages.
Catalog record
| CREATOR | Cornelia Große, Jan Grau, Martin Herzberg, Dietrich H Nies |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 103 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |