Postoperative analgesic effect of intravenous coinjection of lidocaine and dexmedetomidine in gynaecological surgery: a systematic review and meta-analysis
Dan Xie, Fangjun Wang, Wen Wen, Hongqiong Li · 2024
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Description
Dan Xie and co-authors pool trials of two intravenous drugs given as a pair for pain after gynecological surgery, in a systematic review and meta-analysis, published in 2024. Operations such as hysterectomy leave moderate to severe pain, with side effects of their own. Lidocaine and dexmedetomidine each ease pain; the review asks whether the pair beats either drug alone.
Four main sources were searched for randomized trials in which the combined infusion was compared with one drug on its own during surgery. Two reviewers screened studies, pulled their data, and judged bias on their own. Outcomes covered pain relief, opioid use, quality of recovery, and adverse reactions. Results were pooled as standardized differences. The authors frame the synthesis as guidance for anesthetists choosing infusions that spare opioids after such surgery.
Catalog record
| CREATOR | Dan Xie, Fangjun Wang, Wen Wen, Hongqiong Li |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |