Serial Paediatrics Omics Tracking in Myalgic Encephalomyelitis (SPOT-ME): protocol paper for a multidisciplinary, observational study of clinical and biological markers of paediatric myalgic encephalomyelitis/chronic fatigue syndrome in Australian adolescents aged 12–19 years

Natalie Thomas, Tracey Chau, Darcy Tantanis, Katherine Huang, Adam Scheinberg, Paul R Gooley, Elisha K Josev, Sarah J Knight, Christopher W Armstrong · 2024

Read Serial Paediatrics Omics Tracking in Myalgic Encephalomyelitis (SPOT-ME): protocol paper for a multidisciplinary, observational study of clinical and biological markers of paediatric myalgic encephalomyelitis/chronic fatigue syndrome in Australian adolescents aged 12–19 years by Natalie Thomas, Tracey Chau, Darcy Tantanis, Katherine Huang, Adam Scheinberg, Paul R Gooley, Elisha K Josev, Sarah J Knight, Christopher W Armstrong (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11647375.txt.

Description

Natalie Thomas and co-authors set out a study plan for tracking teen ME/CFS in Australia in two thousand twenty-four. The illness, also called chronic fatigue syndrome, can disable teens in a key growth window. Its biology is poorly known, and teens are rarely studied though onset often peaks at their age.

The plan follows patients aged twelve to nineteen plus healthy peers over time. Urine, blood, and immune cells feed deep scans: full genome reads, chemical profiles, and protein counts. Gold-standard clinic and mind tests run alongside. The team hopes the paired data will yield a marker set for the disease, reveal patient subgroups, and show how the illness works.

Catalog record

CREATORNatalie Thomas, Tracey Chau, Darcy Tantanis, Katherine Huang, Adam Scheinberg, Paul R Gooley, Elisha K Josev, Sarah J Knight, Christopher W Armstrong
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE37 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11647375

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