Efficacy of initial combination with belimumab in newly diagnosed childhood-onset lupus nephritis: a single-centre historical control study
Yinv Gong, Shuhua Liu, Haimei Liu, Yu Shi, Yifan Li, Wanzhen Guan, Qiaoqian Zeng, Qianying Lv, Xiaomei Zhang, Qijiao Wei, Jing Chen, Qian Shen, Hong Xu, Li Sun · 2024
Read Efficacy of initial combination with belimumab in newly diagnosed childhood-onset lupus nephritis: a single-centre historical control study by Yinv Gong, Shuhua Liu, Haimei Liu, Yu Shi, Yifan Li, Wanzhen Guan, Qiaoqian Zeng, Qianying Lv, Xiaomei Zhang, Qijiao Wei, Jing Chen, Qian Shen, Hong Xu, Li Sun (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11647295.txt.
Description
Yinv Gong and co-authors present a 2024 journal article on adding belimumab at the start of treatment for childhood lupus kidney disease. The study compared 38 children given the drug plus standard therapy with 63 given standard therapy alone at one center. All were newly diagnosed and aged 5 to 17.
At twelve months, the belimumab group reached the main kidney response in 97.1 percent of cases against 80.0 percent for standard care. Complete response, low disease activity, and remission rates also ran higher. Disease activity scores fell faster, and far more children tapered steroids to a low dose. The authors support early combination use.
Catalog record
| CREATOR | Yinv Gong, Shuhua Liu, Haimei Liu, Yu Shi, Yifan Li, Wanzhen Guan, Qiaoqian Zeng, Qianying Lv, Xiaomei Zhang, Qijiao Wei, Jing Chen, Qian Shen, Hong Xu, Li Sun |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 39 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |