Customised 96-ocular TaqMan (iCAM) microarray PCR card for rapid diagnosis of microbial keratitis

Yunfei Yang, Ahmed Roble, Rashmi Deshmukh, James Myerscough, Martin D Curran, Madhavan S Rajan · 2024

Read Customised 96-ocular TaqMan (iCAM) microarray PCR card for rapid diagnosis of microbial keratitis by Yunfei Yang, Ahmed Roble, Rashmi Deshmukh, James Myerscough, Martin D Curran, Madhavan S Rajan (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11647283.txt.

Description

Yunfei Yang and co-authors validate a rapid PCR card for diagnosing microbial eye infection in a 2024 study. Corneal infection needs fast organism identification, but culture can take up to a week. Their custom card tests one corneal sample against ninety six organisms at once.

Patients referred to a Cambridge hospital gave samples split between the card and standard culture. The card found a causative microbe in the same share of samples as culture, about forty four percent, within six to twenty four hours. Combined, the two methods detected microbes in about two thirds of samples. Agreement between methods was moderate.

Catalog record

CREATORYunfei Yang, Ahmed Roble, Rashmi Deshmukh, James Myerscough, Martin D Curran, Madhavan S Rajan
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE26 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11647283

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