Autophagy modulators in type 2 diabetes: A new perspective
Ayah Talal Zaidalkilani, Hayder M. Al‐kuraishy, Esraa H. Fahad, Ali I. Al‐Gareeb, Yaser Hosny Ali Elewa, Mahmoud Hosny Zahran, Athanasios Alexiou, Marios Papadakis, Ammar AL‐Farga, Gaber El‐Saber Batiha · 2024
Read Autophagy modulators in type 2 diabetes: A new perspective by Ayah Talal Zaidalkilani, Hayder M. Al‐kuraishy, Esraa H. Fahad, Ali I. Al‐Gareeb, Yaser Hosny Ali Elewa, Mahmoud Hosny Zahran, Athanasios Alexiou, Marios Papadakis, Ammar AL‐Farga, Gaber El‐Saber Batiha (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11647182.txt.
Description
Ayah Talal Zaidalkilani and colleagues review the role of autophagy, the cell recycling system, in type two diabetes. Recycling keeps insulin-making cells in the pancreas working and helps body tissues respond to insulin. When recycling falters, those cells struggle and insulin resistance grows. When recycling runs too hot, the same insulin-making cells can die. Writing in twenty twenty-four, the authors survey drugs and compounds that either block or boost recycling, and how each direction might change the course of the disease.
Because the system cuts both ways, timing and dose matter more than a simple on or off choice. The review weighs evidence for modulators as add-on treatments and flags where human data remain thin. Readers get a map of a fast-moving research area and a caution that helpful and harmful effects can come from the same pathway.
Catalog record
| CREATOR | Ayah Talal Zaidalkilani, Hayder M. Al‐kuraishy, Esraa H. Fahad, Ali I. Al‐Gareeb, Yaser Hosny Ali Elewa, Mahmoud Hosny Zahran, Athanasios Alexiou, Marios Papadakis, Ammar AL‐Farga, Gaber El‐Saber Batiha |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |