Metabolomic heterogeneity of ageing with ethnic diversity: a step closer to healthy ageing

Dakshat Trivedi, Katherine A. Hollywood, Yun Xu, Fredrick C. W. Wu, Drupad K. Trivedi, Royston Goodacre · 2024

Read Metabolomic heterogeneity of ageing with ethnic diversity: a step closer to healthy ageing by Dakshat Trivedi, Katherine A. Hollywood, Yun Xu, Fredrick C. W. Wu, Drupad K. Trivedi, Royston Goodacre (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11646956.txt.

Description

Dakshat Trivedi and co-authors profile blood chemistry across ethnic groups in a 2024 paper on healthy ageing. Most studies of body chemistry compare sick and well people, leaving normal ethnic differences poorly mapped. The team focused on community-dwelling men in north-west England.

Serum from 572 men of White European, South Asian, and African-Caribbean backgrounds, aged 40 to 86, was scanned with two high-end methods. Models sorted men by ethnicity with about 90 percent accuracy, and by age group nearly as well. Fats, organic acids, and amino-acid products drove the sorting. Pathway analysis flagged shifts in energy processing and fat building. The authors say such baselines are needed before chemistry-based health tests can be fairly tailored.

Catalog record

CREATORDakshat Trivedi, Katherine A. Hollywood, Yun Xu, Fredrick C. W. Wu, Drupad K. Trivedi, Royston Goodacre
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE49 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11646956

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