PPIH Expression Correlates with Tumor Aggressiveness and Immune Dysregulation in Hepatocellular Carcinoma
Jiaxin Bei, Zihao Sun, Rongdang Fu, Xinkun Huang, Jiabai Huang, Yongyou Luo, Yihu Li, Ye Chen, Zhisheng Wei · 2024
Read PPIH Expression Correlates with Tumor Aggressiveness and Immune Dysregulation in Hepatocellular Carcinoma by Jiaxin Bei, Zihao Sun, Rongdang Fu, Xinkun Huang, Jiabai Huang, Yongyou Luo, Yihu Li, Ye Chen, Zhisheng Wei (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11646373.txt.
Description
Jiaxin Bei and co-authors study a gene called PPIH in liver cancer, in a research paper from 2024. The cancer has complex roots and an immune setting that blunts treatment, so outcomes stay poor. The gene helps fold proteins, and its level in tumors may track how aggressive the cancer is and how immunity behaves.
Data from large cancer and healthy tissue sets show the gene is raised in many cancers. High levels track with poor survival in liver cancer. The team also checks gene silencing marks, mutations, and immune cell entry. Lab and animal tests probe what the gene does in tumor cells. The work marks it as a risk signal.
Catalog record
| CREATOR | Jiaxin Bei, Zihao Sun, Rongdang Fu, Xinkun Huang, Jiabai Huang, Yongyou Luo, Yihu Li, Ye Chen, Zhisheng Wei |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |