Inferring single-cell resolution spatial gene expression via fusing spot-based spatial transcriptomics, location, and histology using GCN

Shuailin Xue, Fangfang Zhu, Jinyu Chen, Wenwen Min · 2025

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Description

Spatial transcriptomics (ST technology allows for the detection of cellular transcriptome information while preserving the spatial location of cells. This capability enables researchers to better understand the cellular heterogeneity, spatial organization, and functional interactions in complex biological systems. However, current technological methods are limited by low resolution, which reduces the accuracy of gene expression levels.

Catalog record

CREATORShuailin Xue, Fangfang Zhu, Jinyu Chen, Wenwen Min
YEAR2025
COLLECTIONPAPERS
FORMATTXT
FILE SIZE93 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11645551

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