Meniere's disease: Structural considerations in early cochlea hydrops
Daniel J Pender · 2024
Read Meniere's disease: Structural considerations in early cochlea hydrops by Daniel J Pender (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11645473.txt.
Description
Daniel Pender analyzes the shape of the inner ear to explain where Meniere's disease begins, in a paper published in 2024. The disease involves endolymphatic hydrops, a swelling of fluid spaces in the cochlea that distorts hearing and balance. Pender argues the swelling's pattern is written into the cochlea's structure: its flattened spiral, the ring shape of the stretched duct, and the stretchiness of Reissner's membrane.
Using dimensions from a normal human cochlea, he computed membrane stress, strain, and displacement turn by turn as the duct inflates into a spiral toroid. Every measure peaked at the apex, the spiral's tip, and was mildest in the lower basal turn. The geometry thus predicts the apex suffers first, a structural susceptibility clinicians can test against imaging.
Catalog record
| CREATOR | Daniel J Pender |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 24 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |