Obesity, Osteoarthritis, and Myokines: Balancing Weight Management Strategies, Myokine Regulation, and Muscle Health
Daniel Vasile Timofte, Razvan Cosmin Tudor, Veronica Mocanu, Luminita Labusca, Lindsay Brown · 2024
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Description
Daniel Vasile Timofte and four co-authors review how obesity and osteoarthritis feed each other, with muscle signals in the middle, in work from 2024. Extra weight speeds joint wear, while sore joints cut activity and deepen obesity. Muscles release myokines during exercise, and three of them, irisin, interleukin-6 and myostatin, steer metabolism, inflammation and tissue repair.
The review argues that supervised weight loss must run beside muscle rehabilitation, not instead of it. Tuning myokine levels through exercise and weight control may soften both conditions at once. The authors map where such combined care could help and where trials are still missing.
Catalog record
| CREATOR | Daniel Vasile Timofte, Razvan Cosmin Tudor, Veronica Mocanu, Luminita Labusca, Lindsay Brown |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 70 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |