A Ratiometric Fluorescent Sensor for the Detection of Norfloxacin in Foods Based on ZIF-8 Core–Shell-Structured Molecularly Imprinted Encoded Microspheres

Ya Chen, Xueyong Qiao, Guoran Sun, Zhonghui Han, Lei Lv, Xiaolei Zhao, Jinxing He · 2024

Read A Ratiometric Fluorescent Sensor for the Detection of Norfloxacin in Foods Based on ZIF-8 Core–Shell-Structured Molecularly Imprinted Encoded Microspheres by Ya Chen, Xueyong Qiao, Guoran Sun, Zhonghui Han, Lei Lv, Xiaolei Zhao, Jinxing He (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11644773.txt.

Description

Ya Chen and co-authors build glowing beads that sniff out an antibiotic hiding in food, in a 2024 study. Norfloxacin residues in meat and milk threaten health and breed resistant bacteria, so inspectors need fast tests. The team's sensor is a tiny sphere with a metal-framework core, wrapped in a polymer stamped with the drug's molecular shape, like a lock cut for one key. Two quantum dots inside glow green and red.

When the drug binds, the red glow dims while the green stays constant, so the colour ratio reports the dose. The response stayed linear across a wide range, with spiked recoveries near one hundred percent in chicken, pork, fish, and milk, and a detection limit of two micrograms per litre. A two-colour readout guards against the false alarms that plague single-signal tests.

Catalog record

CREATORYa Chen, Xueyong Qiao, Guoran Sun, Zhonghui Han, Lei Lv, Xiaolei Zhao, Jinxing He
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE31 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11644773

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