Evaluation of the Leaves and Seeds of Cucurbitaceae Plants as a New Source of Bioactive Compounds for Colorectal Cancer Prevention and Treatment
Mercedes Peña, Ana Guzmán, Cristina Mesas, Jesús M. Porres, Rosario Martínez, Francisco Bermúdez, Consolación Melguizo, Laura Cabeza, Jose Prados · 2024
Read Evaluation of the Leaves and Seeds of Cucurbitaceae Plants as a New Source of Bioactive Compounds for Colorectal Cancer Prevention and Treatment by Mercedes Peña, Ana Guzmán, Cristina Mesas, Jesús M. Porres, Rosario Martínez, Francisco Bermúdez, Consolación Melguizo, Laura Cabeza, Jose Prados (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11644257.txt.
Description
Peña and eight co-authors test extracts from gourd family plants against colon cancer cells in this two thousand twenty-four study. Leaves and seeds of these plants carry compounds with reported antioxidant and antitumor effects, yet the family is underexplored for cancer uses.
From several extracts, cold alcohol extracts of leaves and seeds from two Cucurbita lines stood out, strongly slowing three colon cancer cell lines without harming liver cells. They stalled cell division, triggered cell death, and blocked colony growth and blood vessel signals, partly through phenolic and triterpenoid compounds the team identified. A mild boost appeared when one extract joined the drug oxaliplatin. The work nominates these farm plants as sources for new preventive or supporting treatments.
Catalog record
| CREATOR | Mercedes Peña, Ana Guzmán, Cristina Mesas, Jesús M. Porres, Rosario Martínez, Francisco Bermúdez, Consolación Melguizo, Laura Cabeza, Jose Prados |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 34 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |