A Novel Polymer Film to Develop Heart Valve Prostheses

Irina Yu. Zhuravleva, Anna A. Dokuchaeva, Andrey A. Vaver, Ludmila V. Kreiker, Alexandra B. Mochalova, Elena V. Chepeleva, Maria A. Surovtseva, Aleksei N. Kolodin, Elena V. Kuznetsova, Rostislav I. Grek · 2024

Read A Novel Polymer Film to Develop Heart Valve Prostheses by Irina Yu. Zhuravleva, Anna A. Dokuchaeva, Andrey A. Vaver, Ludmila V. Kreiker, Alexandra B. Mochalova, Elena V. Chepeleva, Maria A. Surovtseva, Aleksei N. Kolodin, Elena V. Kuznetsova, Rostislav I. Grek (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11644251.txt.

Description

Irina Zhuravleva and co-authors test a polymer film for building artificial heart valves in a 2024 study. Valves made from preserved animal tissue wear out as calcium builds up in the dead tissue. That limit bites harder as catheter-delivered valves spread. A tough polymer leaflet could sidestep the decay, if the material proves friendly to blood and cells.

The film, sold under the name REPEREN, is cast from acrylic building blocks and reinforced with hair-thin polyamide fibers. The team mapped its surface with two kinds of microscopes. They measured how well water spreads on it, whether vessel-lining cells grow on it in culture, and how blood platelets react to it, a first test of clotting risk. The study lays the groundwork for shaping the film into valve leaflets.

Catalog record

CREATORIrina Yu. Zhuravleva, Anna A. Dokuchaeva, Andrey A. Vaver, Ludmila V. Kreiker, Alexandra B. Mochalova, Elena V. Chepeleva, Maria A. Surovtseva, Aleksei N. Kolodin, Elena V. Kuznetsova, Rostislav I. Grek
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE38 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11644251

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