Nutritional Genomics: Implications for Age-Related Macular Degeneration

Inês Figueiredo, Cláudia Farinha, Patrícia Barreto, Rita Coimbra, Pedro Pereira, João Pedro Marques, Isabel Pires, Maria Luz Cachulo, Rufino Silva · 2024

Read Nutritional Genomics: Implications for Age-Related Macular Degeneration by Inês Figueiredo, Cláudia Farinha, Patrícia Barreto, Rita Coimbra, Pedro Pereira, João Pedro Marques, Isabel Pires, Maria Luz Cachulo, Rufino Silva (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11643977.txt.

Description

Inês Figueiredo and co-authors present a narrative review, published in 2024, on matching diet advice to genes in a leading cause of vision loss. Age-related macular degeneration damages the center of the retina in older adults, driven by genes, environment, and diet together. Nutritional genomics studies how gene variants change what nutrients do, and the review asks what that means for this disease.

Landmark supplement trials showed certain vitamins and minerals slow progression to advanced disease. Gene findings now refine that picture: variants in one immune gene may strengthen zinc's calming effect, while a fat handling gene changes responses to omega-3 fats. The authors chart a path toward eye care diets tuned to each patient's genetic profile.

Catalog record

CREATORInês Figueiredo, Cláudia Farinha, Patrícia Barreto, Rita Coimbra, Pedro Pereira, João Pedro Marques, Isabel Pires, Maria Luz Cachulo, Rufino Silva
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE63 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11643977

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