Weizmannia coagulans BC99 Enhances Intestinal Barrier Function by Modulating Butyrate Formation to Alleviate Acute Alcohol Intoxication in Rats
Cheng Li, Shirui Zhai, Mengyao Duan, Li Cao, Jie Zhang, Yao Wang, Ying Wu, Shaobin Gu · 2024
Read Weizmannia coagulans BC99 Enhances Intestinal Barrier Function by Modulating Butyrate Formation to Alleviate Acute Alcohol Intoxication in Rats by Cheng Li, Shirui Zhai, Mengyao Duan, Li Cao, Jie Zhang, Yao Wang, Ying Wu, Shaobin Gu (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11643948.txt.
Description
Cheng Li and co-authors test a probiotic strain against acute alcohol poisoning in rats. A drunk gut leaks, letting bacterial toxins slip into the blood and inflame the liver. The strain, a spore forming microbe, was fed to rats before heavy alcohol doses. The team tracked how fast the rats sobered and how their organs fared.
Treated rats stayed sober longer before tipping over, in plain terms their drunk onset slowed. Liver harm, gut leak, and blood toxin levels all eased. The microbe shifted gut flora toward groups that make butyrate, a gut wall fuel. Feeding butyrate alone copied much of the gut protection. The authors trace the benefit to this gut wall route.
Catalog record
| CREATOR | Cheng Li, Shirui Zhai, Mengyao Duan, Li Cao, Jie Zhang, Yao Wang, Ying Wu, Shaobin Gu |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 42 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |