Human birth tissue products as a non-opioid medicine to inhibit post-surgical pain
Chi Zhang, Qian Huang, Neil C Ford, Nathachit Limjunyawong, Qing Lin, Fei Yang, Xiang Cui, Ankit Uniyal, Jing Liu, Megha Mahabole, Hua He, Xuewei Wang, Irina Duff, Yiru Wang, Jieru Wan, Guangwu Zhu, Srinivasa N Raja, Hongpeng Jia, Dazhi Yang, Xinzhong Dong, Xu Cao, Scheffer C Tseng, Shaoqiu He, Yun · 2024
Read Human birth tissue products as a non-opioid medicine to inhibit post-surgical pain by Chi Zhang, Qian Huang, Neil C Ford, Nathachit Limjunyawong, Qing Lin, Fei Yang, Xiang Cui, Ankit Uniyal, Jing Liu, Megha Mahabole, Hua He, Xuewei Wang, Irina Duff, Yiru Wang, Jieru Wan, Guangwu Zhu, Srinivasa N Raja, Hongpeng Jia, Dazhi Yang, Xinzhong Dong, Xu Cao, Scheffer C Tseng, Shaoqiu He, Yun (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11643635.txt.
Description
Zhang and co-authors test in 2024 whether products made from human birth tissue can ease pain after surgery without opioids. Pain after operations is a heavy burden, and opioids carry grave side effects. A membrane product from the womb lining had shown early promise in the clinic.
In mice, the product applied at the wound dulled lasting pain sensitivity, with no opioid like harms. It worked by quieting pain sensing nerve cells through a surface gate. The team then purified the active matrix part, which beat the raw product in purity and ease of use. The pure part reshaped cell scaffolds and cut nerve firing.
Catalog record
| CREATOR | Chi Zhang, Qian Huang, Neil C Ford, Nathachit Limjunyawong, Qing Lin, Fei Yang, Xiang Cui, Ankit Uniyal, Jing Liu, Megha Mahabole, Hua He, Xuewei Wang, Irina Duff, Yiru Wang, Jieru Wan, Guangwu Zhu, Srinivasa N Raja, Hongpeng Jia, Dazhi Yang, Xinzhong Dong, Xu Cao, Scheffer C Tseng, Shaoqiu He, Yun |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 96 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |